![]() ![]() If implementing PaperCut NG/MF for the first time it is recommended to plan a simple configuration in the first phase, then return to implement find me printing or load balancing in a later phase once users and administrators are comfortable with the basic features. The topics covered in this section are relatively advanced in nature and targeted towards the administrator who is already comfortable with PaperCut NG/MF and print queue configuration. These topics are addressed together in this section as they both involve the concept of print job redirection, where a job is taken from one queue and transferred to another. Many of the advanced tools are written for software and script developers. This is the recommended approach because it allows the card/ID numbers to be associated with users in a centralized location. Other technologies that PaperCut NG/MF supports are: PaperCut NG/MF provided technologies. PaperCut NG/MF can import user card/ID numbers from Active Directory and LDAP. It can be installed on its own or work together with PaperCut NG/MF. However, if used incorrectly, these tools could lead to unexpected results. PaperCut’s solution for mobile and BYOD printing is a product called Mobility Print. Printer load balancing - covers the act of automatically distributing print load between multiple physical printers. The advanced tools provided with PaperCut NG/MF are very powerful and offer opportunities for all manner of customizations and enhancements. A tour of PaperCut NG and PaperCut MF, installation instructions, configuration instructions, system and server. ![]() It’s sometimes referred to as “Pull Printing” or “Push Printing”. It is used in a wide variety of environments ranging from universities with large printer fleets supporting over 100,000 users to smaller organizations that track printing for a fewer than 50 users on 3 or. It is a roaming print service that allows print jobs to find users based on their physical location. PaperCut NG/MF is designed for flexibility and scalability and can be configured to meet your print management needs now and in the future. Set the secondary sync source (optional) Set the sync options. So if you cant find what youre looking for in the KB, its worth checking the help centers too, for example, the PaperCut NG/MF manuals, the Mobility. To synchronize your user data with Active Directory: Set the primary sync source. This section covers two powerful features: printer load balancing and “Find-Me” printing.įind-Me printing-solves the problem of finding the closest printer from a long list of available printers. PaperCut NG/MF’s Active Directory integration is performed at a native level and supports advanced features, such as nested groups and OU’s. PRODUCTS FEATURED Find-Me printing and printer load balancing ![]()
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![]() When you can laugh at life, you feel less stressed. Give yourself permission to smile or laugh, especially during difficult times. If you find that your thoughts are mainly negative, try to find a way to put a positive spin on them. ![]() Periodically during the day, stop and evaluate what you're thinking. Think of a positive thought to manage your stress instead of a negative one. You can start small by focusing on one area to approach in a more positive way. If you want to become more optimistic and engage in more positive thinking, first identify areas of your life that you usually think negatively about, whether it's work, your daily commute, life changes or a relationship. Following are some ways to think and behave in a more positive and optimistic way: The process is simple, but it does take time and practice - you're creating a new habit, after all. You can learn to turn negative thinking into positive thinking. You see things only as either good or bad. Keeping impossible standards and trying to be more perfect sets yourself up for failure. You make a big deal out of minor problems. You think of all the things you think you should do and blame yourself for not doing them. You avoid being responsible for your thoughts and feelings. You try to say someone else is responsible for what happened to you instead of yourself. The drive-through coffee shop gets your order wrong, and then you think that the rest of your day will be a disaster. You automatically anticipate the worst without facts that the worse will happen. For example, you hear that an evening out with friends is canceled, and you assume that the change in plans is because no one wanted to be around you. ![]() ![]() When something bad occurs, you automatically blame yourself. That evening, you focus only on your plan to do even more tasks and forget about the compliments you received. You completed your tasks ahead of time and were complimented for doing a speedy and thorough job. For example, you had a great day at work. You magnify the negative aspects of a situation and filter out all the positive ones. Not sure if your self-talk is positive or negative? Some common forms of negative self-talk include: ![]() ![]() ![]() This acquisition was made purely for football games like this one, contests where physicality and toughness reign supreme in terms of deciding a winner. In the off-season the Rams added Bobby Wagner, and now have one of the best run stuffing linebackers in NFL history at their disposal. When the Rams defeated San Francisco in the Championship game, SF only had 20 rushing attempts for 50 yards, providing a clear cut recipe on how to beat the 49ers. In the second meeting, the 49ers had 31 rushing attempts for 135 yards en route to a regular season sweep of the Rams. In last season's Monday night football meeting between the Rams and Niners, San Francisco did just that, as they ran the ball a whopping 44 times for 156 yards during the 31-10 win against Los Angeles. They want to run the football, then run the football, and then run the football some more. There are absolutely zero secrets as it pertains to the San Francisco 49ers offensive philosophy under coach Kyle Shanahan. 3 REASONS THE RAMS WILL WINġ) DEFENSE DOMINATES RUN GAME Photo by Michael Owens/Getty Images Here are 3 reasons why they WILL win and make the most of the opportunity, as well as 3 things that could lead to a disappointing loss. The Rams (2-1) have the best record in the West while the 49ers (1-2) have the same record as both the Seahawks and the Cardinals, so Monday night is a shot for the Rams to take control of the division. Now, all eyes are on the first meeting between the two squads since that Championship contest. Trey Lance ended up suffering a season-ending injury just one quarter into Week 2 this season, pushing Jimmy Garoppolo back into the starting job for San Francisco. ![]() However, Garoppolo and the 49ers figured out a deal to keep the QB in town for another season as an insurance option for their young QB Trey Lance, and boy are they happy they did so. The game was an instant classic, and it also seemed as if it was the end of the Jimmy G era for the 49ers, as third overall pick in the 2021 NFL Draft Trey Lance was catapulted into the starting quarterback role basically immediately following the loss for the Niners. Just 9 months ago, the Los Angeles Rams defeated the San Francisco 49ers in the NFC Championship game to punch their ticket to Super Bowl 56. ![]() ![]() Resident Evil has an incredible array of options in order to customize one’s visual experience.No lagging or considerable issues with the Xbox One X or Xbox One.The base Xbox does not quite match the higher framerate if the base PS4.The Xbox One X has the best frame rate and resolution of all four console options.In a humorous turn of events, the base Xbox shows considerable reconstruction whereas the PS4 does not.The Xbox One X has virtually no visible reconstruction, unlike the PS4 Pro, which does have this issue.The motion blur effect is better on the Xbox One X than on the base console.The Xbox One and Xbox One X, although not as “sharp as the PS4, have “cleaner” pictures due to effective aliasing.Ironically, the Xbox One X has the most stable framerate of all four consoles, consistently staying at 60 FPS with relatively infrequent and small drops.The base console has incredibly severe and wildly erratic dips in framerate, the worst of all four console options.The Xbox One X has a 2880 x 1620 resolution. ![]() On the basic Xbox One, you will experience a 1920 x 1080 resolution.No lagging or noticeable issues with performance on either the PS4 or PS4 Pro.The Xbox One X has a much more consistent framerate than the PS4 Pro, but the base PS4 suffers less frequent and less significant dips in FPS than the base Xbox One.The PS4 Pro maintains a relatively consistent framerate, while the PS4 itself is incredibly inconsistent.The base PS4 shows little reconstruction, but the base Xbox does quite a bit.The PS4 Pro does show visible reconstruction artifacts whereas the Xbox One X does not.The quality of the motion blur effect is better on the PS4 Pro than the base console, as you might imagine.Despite this, the PS4 looks less “clean” due to frequent issues with aliasing. The game will look “sharper” than on the Xbox One, which does look a little bit blurrier.It will occasionally dip, but not too much. On the PS4 Pro, the frame rate is pretty consistent at 60 FPS.For the most part, the frame rate will stay in the 50s, but it will continually dip into the 40s and sometimes the 30s. On the basic console, the frame rate is incredibly erratic. ![]() The PS4 Pro has a 2880 x 1620 resolution.On the basic PS4, you will experience a 1920 x 1080 resolution.This article is meant to help you determine which version of Resident Evil 2 is best for you to play. The Playstation 4, the Xbox One, and PC all have their own benefits and disadvantages. That doesn’t mean, however, that your experience can’t be optimized. Regardless of what platform you choose, Resident Evil 2 is an amazing game. ![]() What platform should I play Resident Evil 2 REmake on? ![]() ![]() Itâs important to note that SSH tunneling is frequently used by hackers, who build backdoors in internal networks so that attackers can easily access internal data. SSH keys use asymmetric encryption and provide an even higher level of security. SSH tunnels also offer increased security when youâre surfing on unfamiliar networks, for example in a hotel or coffee shop. A SSH File Transfer Protocol, SFTP for short, will be used for this. Since the Raspberry Pi 4 will be dropped on the back of a system (or switch) inside an organization, we wonât be able to directly connect to it. If youâre transporting data from services that use an unencrypted protocol, you can use SSH forwarding to encrypt the data transfer. While we can do a reverse SSH shell to access our Raspberry Pi 4 device, we will also configure the device to use a reverse OpenVPN connection over port 443 (HTTPS). This is similar to a Virtual Private Network (VPN) but is nonetheless different - try not to mix the two up. It will look like you are on this network, when you are in reality just accessing it using the SSH tunnel. ![]() The use of this virtual network allows certain restrictions on access to be bypassed. ![]() Once established, it will stop printing 'Attempting connection' and will hang. The script will attempt to connect to the server until it establishes a connection with it. ![]() The reverse SSH tunnel looks like this: laptop (SFTP client)->nat->middleman<-nat<-desktop (SFTP server) On laptop edit /.ssh/config and add this: Host SftpToDesktop HostName localhost Port p User admin. Step 3: Set Up a Connect Listener on Your Client/Pi. In most cases, SSH port forwarding is used to create an encrypted connection between a local computer (the local host) and a remote computer. First, this is a prerequesite (at least for me): Remote desktop over SSH reverse tunnel to replace TeamViewer. Send email to have the museum staff verify that a "good" video is playing.There are various use cases for secure shell port forwarding. Move the previous video to a backup file. Have the museum staff send the email to a script strip off the video from the email and de-encode it back to it's original format. Set up an incoming mail server on the video machine. To configure a reverse SSH tunnel, navigate to the Admin Console by clicking on the Admin tab from the top navigation bar. ![]() You would then have some way of triggering a script that would create the tunnel (bonus points for random ports on the tunnel, communicated to you by the video machine sending an email (more bonus points for encrypting that email) to you that it's ready).Īnother solution, channeling the ghost of Reuben Garrett Lucius Goldberg. Then instead of emailing you the video, the museum staff would simply stick it on a USB drive themselves and insert the drive in the computer. Have the tunnel on a "timer" (say connects every day at 8 PM.Īn example of Number 2 would be to have the tunnel created whenever someone sticks a USB device into the machine.Have some mechanism of triggering the creation of the tunnel.Leave the tunnel up all the time (meaning have some sort of script that restarts it).Yeah, it can get confusing the first 100 or so times you do it. Then you ssh/scp from your computer to the port that is established by the tunneling command. This is known as "reverse ssh tunneling", and basically what you do is on the museum computer you run a ssh -R command that causes a tunnel to get set up from inside their firewall to your computer. If I read the question, including the title properly, you are asking how connect from the museum computer to your computer so you can copy a video up. ![]() ![]() RPG Site: I did run into Feedback Billy (an NPC) when I was playing through the game on the show floor, that's an interesting thing that I hadn't seen before. Unless we get a lot of feedback through tools like Game Preview, which is a great tool to have for something like this. Michael Douse: On PC you can actually toggle between the two versions of the game completely, journal and all. RPG Site: On PC will I be able to swap back to the old version of the journal, or is it a switchover? So you don't have to read reams of text for the same amount of information. Michael Douse: It's the same style of writing, but mainly we've made it shorter. RPG Site: So is it more task-oriented, or bulleted? The current journal oftentimes gives you hints or implies what needs to be done, without telling you what exactly needs to be done. We wanted to make it a lot easier to understand. On PC, let's call the journal a mess, there were a lot of words and a lot of text and it was very difficult to follow. One of the other ones we wanted to fix was the Journal system. ![]() For instance, the Definitive Edition will include the Party Inventory system, which will allow players to manage their party from one screen instead of having to move from character to character. ![]() Michael Douse: Well, when the game launched on PC, you could already play with a controller on a couch, so a lot of the things are actually the same, but we've made them better. What changes have been made in the Definitive Edition with respect to how the game looks and plays with this in mind? For a console version, not only do you play with a controller, but also on a larger screen from further away. RPG Site: When I personally sit down to play an (isometric) game like Divinity, I feel most comfortable with a mouse and keyboard. Just like those games, we saw this an opportunity to bring those experiences to more people, even though it might be slightly unfamiliar to Namco's usual catalog. Michael Douse: While Namco didn't publish Original Sin I, they do have experience working with games like Witcher 2 and Dark Souls, games that are also very much their own things. RPG Site: Why is Divinity: Original Sin II a fit for Bandai Namco to publish on consoles? At E3 2018, we had a chance to talk to Larian Publishing Director Micheal Douse about bringing the 2017 RPG of the Year contender to Playstation 4 and Xbox One, and also about the partnership with Bandai Namco for this project. ![]() ![]() In this video tutorial you will learn how to add a simple grain texture to … Find & Download the most popular Vintage Texture Vectors on Freepik Free for commercial use High Quality Images Made for Creative Projects Download this Free Vector about White grunge distressed texture set, and discover more than 66 Million Professional Graphic Resources on Freepik. Celebrating a huge selection of authentic textures, these halftone vector brushes are ideal for adding everything from bold, grunge shading and drop shadows to subtle speckle accents and detailed … I am struggling with cutting an object from illustrator (a circle with light globes around it emitting light in the form of a gradient) and posting it into another illustrator file. I will share with you 2 ways to add texture to your illustration in Adobe Illustrator by using nois These brushes are perfect for shading, or simply adding some texture or noise to your artwork. Illustrator will remember the last gradient used, so you should have the same gradient fill from the first rectangle. The first picture below is the 4圆 and the second is scaled up to 18x24 Is there a way for me You can take your illustration or project to the next level by adding a bit of texture. When the Appearance box appears, click on the effect you wish to remove. I hope this video will inspire you to create more designs wit Pro-Quality Textures, Brushes, and Effects for Procreate, Photoshop, Illustrator, Clip Studio Paint and Affinity. This can be true, except for the sound part, if you use our wooden textures, which work great as backgrounds and look very realistic. Fill it with Cyan from the “Swatches Panel”. Apply to any vector fill, group, editable text, image object or targeted layer. ly/3lR3INj □□□ Premium Tutorials : □⭐⭐ YouTub Paper Texture Vector Images - 316,822 royalty free vector graphics and illustrations matching Paper Texture. With the texture selected, create a Linear Gradient (>) from the Gradient Panel and take off the stroke. ![]() Using the Rectangle Tool, create a square and position it to the center of the board. Step 3 : apply grain from the effect menu > textures > grain Unlimited Downloads of 2,000,000+ Brushes, Fonts, Graphics & Design Templates Ad. 83,000+ Vectors, Stock Photos & PSD files. Wood Grain is a collection of over 70 high-resolution organic wood and timber textures and stamp brushes ready for use in your favorite design apps. Add a Noise filter to the photo grain texture layer by going to Filter > Noise > Add Noise in the top menu bar. Select the new fill and apply your pattern from the Swatches panel. com/products/illustra In this tutorial, I show you how to make a basic wood grain style texture that you can use for illustration or any design work. Modern Woodcut – Adobe Illustrator Brushes $ 19. After cycling through the options in the Grain type menu, I settled on Contrasty, with the … Backgrounds, patterns, visual effects, illustrations: textures give life to all types of resources. A little … In today's Adobe Illustrator tutorial you'll learn 3 ways to add grain texture without any brushes and how to texture illustration easily with full control on each texture effect you With the gradient selected, go Effect > Texture > Grain. #adobeill You can find & download the most popular Grain Texture Vectors on Freepik. ![]() ![]() A little window will pop up giving you some options to play with. Welcome to our community of 19+ million annual readers, we are so grateful to have you When I get back to my artboard, I set the transparency of the Grain to "Soft Light. In this case i will make mine at 800 x 600 px. ![]() However, a warning: Illustrator’s built-in textures kind of suck. Free for commercial use High Quality Images This would be another example, just finer texture: It's an old technique, where sign artists, etc would probably take spray paint and spray the noisy, gradient texture over masked off portions of the canvas/sign. ![]() ![]() ![]() Credits and personnel Ĭredits transcribed from the liner notes of Elevate. However, they have said that they completely re-recorded the song, and have teased an eventual release of their new, re-imagined version. According to Carlos PenaVega, "Show Me" was the only song on the 2021 setlist that they were unable to obtain the original stems for, so they were forced to re-record a new version to use as a backing track. "Show Me" was performed on both the Better with U Tour and Big Time Summer Tour, as well as in the 2021 Big Time Rush Live shows. In its inclusion on Elevate's track listing, Schmidt described the song as bringing "a level of maturity" as well as "maybe a little. He and Logan Henderson were particularly interested in recording the track, with Henderson saying that, upon his first time hearing the track, he knew that "this song has to be on the album to make this album complete," additionally recalling thinking "it will complete the story if we have this song." Kendall Schmidt and James Maslow each said that they were "kind of on the ropes" about the track at first, but once they entered the studio and recorded their own vocals, all four members were "100% on board." Īccording to Carlos PenaVega, it took them a long time to convince writer and producer Lucas Secon to let them cut "Show Me", which he had originally showed them about "a year and a half" before the release of Elevate. In 2016, Palmer uploaded the unreleased album herself via Soundcloud, though "Show Me" was not included. While Palmer's single leaked onto the Internet in September 2011, the album was ultimately shelved, and the song never officially released. And then it also could be like let me show you." "It’s like, show me the kind of guy that I should be with. She described "Show Me" as a "little flirty song" with "a pop and R&B feel," saying it represented "definitely the older me." Lyrically, she explained how the song "can be seen in different types of ways." ![]() Initially teasing a release between late 2011 and spring 2012, the singer also confirmed plans for an accompanying music video. Palmer recorded the song with producer Lucas Secon in June 2011. ![]() It was intended to be the lead single for her self-titled sophomore album, planned for release via Interscope Records. "Show Me" was originally recorded by American actress and singer Keke Palmer. ![]() ![]() Toggle this option on or off depending on what you prefer.Scroll down and find the “Send Read Receipts” option. Read receipts are enabled by default and available in one-to-one conversations, or in groups with less than twenty participants.In other words, this will enable or disable this for everyone who texts you. This will enable or disable read receipts for all messages. Turn Off Read Receipts for Specific Contacts. Disabling (Or Enabling) Read Receipts for Individual Contacts First, open any conversation thread in the Messages app. It's a really simple process, so let's get started. How to enable or disable read receipts for all conversationsįollow the steps below. To enable read receipts for everyone who texts you go to Settings > Messages on your iPhone. As long as you're running iOS 10 or higher on your iPad, iPhone, or iPod touch, you can pick and choose which contacts have Read Receipts enabled or disabled. Please also note that, like iMessage, many other messaging services such as WhatsApp, Facebook Messenger, Instagram, support read receipts. See also: Messages Read Receipts Not Working, Fix When this feature is disabled, messages you send will only show up as “Delivered,” not “Read” and the people will not know when or if you read their message. When this feature is enabled, people will see when you’ve read their messages. This article details how you can do this. From there, check to see if Send Read Receipts are enabled for this/these contact (s). Additionally, you can turn this off or on for specific contacts or across the board. If the issue is with specific contacts, you may want to open the iMessage, tap on their name at the top of the message, and then tap information. Android: Open Messages, tap three vertical dots, and select Settings. You can also change this setting on your Mac. What to Know iPhone: Go to Settings > Messages > toggle on Read Receipt. You can turn on or off read receipts on your iPhone or iPad from the settings menu. Several people want to turn this feature is off because this feature will let someone know that you view the messages he or she send but not necessarily respond in a timely manner. Unless this is turned off, iMessage delivers read reports that say a contact you have read the message you have received. Read receipts are not going to work if you or your recipients are using a non-Apple device. I have done some looking around for resolutions, and I have not found a permanent fix. However, it randomly re-starts showing Read Receipts, without warning (and the setting still shows as OFF). See also: iMessage Frequently Asked Questions I am usually able to resolve this (temporarily) by toggling the Read Receipts setting on and off a couple of times. ![]() This note will also include the time you read the message. This read message will appear only if the recipient has his or her read receipts turned on. The recipient has opened (presumably read) your message. ![]() This means that the message was successfully delivered to your recipient’s phone. There are two gray/blue status messages that will appear under each iMessage you send: There may be scenarios where you may not want to send read receipts. Read receipts: In Messages and iMessages, go to Settings > Message > Send Read Receipts or simply search for receipts. Go to Settings > Messages > move the slider next to Send Read Receipts to OFF Position. Click here to see how to tell the difference between an iMessage and an SMS.A read receipt confirms that your iMessage was opened. Enable Read Receipts for Individual Contacts On iPhone 1. You will not be able to adjust the read receipt settings for group messages, or for regular SMS text message conversations. Next, tap the toggle by Send Read Receipts to enable read receipts for that individual contact. This will only work for iMessage conversations with individual contacts. Open the contact in the Messages app by tapping the contact's icon. The steps in this article were written using an iPhone 5, in iOS 10. Turn Read Receipts On or Off for a Conversation on an iPhone in iOS 10 So if you have already updated to iOS 10, continue reading below to learn how you can change your settings. Because of this “all or nothing” distinction, many users would choose to turn off those receipts.īut iOS 10 has changed the way that read receipts work on your iPhone, and you can now change the setting for each individual iMessage conversation. ![]() While you might not have a problem with your close friends or family members knowing that you have read their messages, a work colleague or casual acquaintance might not need to know that. Previously the Read Receipt option had been one that was either on or off for every iMessage that you read on your iPhone. The ability to know that someone has read your message can be very useful when you are transmitting important information. Read receipts are an interesting part of the iMessage experience for iPhone users. ![]() ![]() ![]() ![]() ![]() Farxiga is not indicated to reduce the risk of CV events, CV death or hHF. DECLARE is paving the way for three Phase III trials: Dapa-HF, DELIVER and Dapa-CKD.įarxiga is a first-in-class, oral, once-daily selective inhibitor of human sodium-glucose co-transporter 2 (SGLT2) indicated as both monotherapy and as part of combination therapy to improve glycaemic control, with the additional benefits of weight loss and blood pressure reduction, as an adjunct to diet and exercise in adults with T2D. The DapaCare clinical programme will generate data across a spectrum of people with CV risk factors, established CV disease and varying stages of renal disease, both with and without T2D. 8ĭECLARE is part of the extensive DapaCare clinical programme for Farxiga, which will enrol patients in randomised clinical trials, including a wide range of mechanistic studies, and is supported by a multinational real-world evidence study (CVD-REAL). ![]() DECLARE included more than 17,000 patients across 882 sites in 33 countries and was independently run in collaboration with academic investigators from the TIMI study group (Boston, USA) and the Hadassah Hebrew University Medical Center (Jerusalem, Israel). The results from this landmark trial are especially important since heart failure is an early and frequent complication of diabetes and associated with hospitalisations that result in a considerable societal and economic burden.” 1-7ĭr Stephen Wiviott of Brigham and Women’s Hospital and Harvard Medical School, a senior investigator with the Thrombolysis in Myocardial Infarction (TIMI) study group and co-principal investigator of the trial, commented: “The DECLARE-TIMI 58 results offer compelling evidence that dapagliflozin helps to address an important medical need among a diverse group of patients with type-2 diabetes by reducing the composite of hospitalisation for heart failure or CV death, with a safety profile supportive of broad use.”ĭetailed trial results will be presented on 10 November at the American Heart Association Scientific Sessions 2018 in Chicago, USA.ĭECLARE (Dapagliflozin Effect on Cardiovascular Events)-TIMI 58 is an AstraZeneca-sponsored, randomised, double-blinded, placebo-controlled, multicentre trial designed to evaluate the effect of Farxiga compared with placebo on CV outcomes in adults with T2D at risk of CV events, including patients with multiple CV risk factors or established CV disease. Additionally, fewer MACE events were observed with Farxiga for the other primary efficacy endpoint, however, this did not reach statistical significance.ĭata from DECLARE-TIMI 58 confirmed the well-established safety profile of Farxiga.Įlisabeth Björk, Vice President, Head of Cardiovascular, Renal and Metabolism, Global Medicines Development said: “ Farxiga has achieved a statistically-significant and clinically-important reduction in hospitalisation for heart failure or CV death in a broad range of patients with type-2 diabetes and cardiovascular risk. Farxiga achieved a statistically-significant reduction in the composite endpoint of hospitalisation for heart failure (hHF) or CV death, one of the two primary efficacy endpoints. In the DECLARE (Dapagliflozin Effect on Cardiovascular Events)-TIMI 58 trial, Farxiga met its primary safety endpoint of non-inferiority for major adverse cardiovascular events (MACE). placebo over a period of up to five years, across 33 countries and in more than 17,000 adults with type-2 diabetes (T2D) who have multiple CV risk factors or established CV disease. The trial evaluated the CV outcomes of Farxiga vs. Partnerships, alliances and recognitionĪstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular (CV) outcomes trial (CVOT) for Farxiga (dapagliflozin), the broadest SGLT2 inhibitor CVOT conducted to date.In addition, we have used our large database of clinical findings, biomarkers, and genotypes to enhance the understanding of cardiovascular disease and its risk factors.īy leading large-scale, international, randomized controlled trials of novel therapeutics and performing sophisticated analyses, we have been privileged to help shape the very practice of cardiovascular medicine for over a quarter of a century. We investigate a broad array of therapeutic interventions in individuals across the spectrum of cardiovascular disease, ranging from prevention in those with risk factors, to emergent interventions in those with acute manifestations of disease. Trials have been conducted in over 50 countries and at more than 5000 separate sites. We have led a wide array of trials, from phase I to phase IV, enrolling from less than 30 to more than 26,000 subjects, and with both industry and NIH support. Since its inception in 1984, the TIMI Study Group has been an Academic Research Organization dedicated to advancing the knowledge and care of patients suffering from cardiovascular disease and its risk factors. ![]() |
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